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P1078 / TB APPRISE: TB Ante vs. Postpartum Prevention with INH in HIV Seropositive mothers and their Exposed infants

A Phase IV Randomized Double-Blind Placebo-Controlled Trial to Evaluate the Safety of Immediate (Antepartum-Initiated) Versus Deferred (Postpartum-Initiated) Isoniazid Preventive Therapy Among HIV-infected Women in High TB Incidence Settings

Study Chair

DAIDS Medical Officer

Clinical Research Manager

Consultant

Data Manager

Immunologist

Laboratory Data Manager (LDM)

Laboratory Specialist

Laboratory Technologist

Protocol Pharmacist

Virologist

Westat Representative

Manuscripts

Abstracts

Pharmacokinetic-Pharmacogenetic-Pharmacodynamic analysis of INH and EFV for predicting adverse pregnancy outcomes in women with HIV

Conference

The Union World Conference on Lung Health

Study

P1078

Authors

Aaron L, Montepiedra G, Gausi K, Denti P, Browning R, Theron G, Weinberg A, Nematadzira T, Gupta A, IMPAACT P1078 TB APPRISE Study Team

Pharmacokinetics of isoniazid preventative therapy among HIV-infected pregnant women in high tuberculosis incidence settings

Conference

Population Approach Group in Europe (PAGE) Meeting

Study

P1078

Authors

Kamunkhwala Gausi, Lubbe Weisner, Jennifer Norman, Carole L. Wallis, Carolyne Onyango-Makumbi, Tsungai Chipato, Gerhard Theron, David W. Haas, Timothy R. Sterling, Renee Browning, Nahida Chakhtoura, Adriana Weinberg, Grace Montepiedra, Amita Gupta, Paolo Denti

Maternal IPT in pregnancy and growth faltering among HIV-exposed uninfected infants

Conference

CROI 2022

Study

P1078

Authors

Ashenafi S Cherkos, Sylvia M. LaCourse, Daniel A Enquobahrie, Grace Montepiedra, Caroline Onyango, Blandina T. Mmbaga, Tichaona Vhembo, Gaerolwe Masheto, Gerhard Theron, Adriana Weinberg, Amita Gupta, IMPAACT P1078 TB APPRISE Study team

The Effect of HIV and Latent Tuberculosis Infection During Pregnancy on Infant Immune Development

Conference

International Workshop on HIV Pediatrics

Study

P1078

Authors

Kimberly Shankwitz, Lesley de Armas, Alexander Kizhner, Suresh Pallikkuth, Rajendra Pahwa, Grace Montepiedra, Mauricio Pinilla, Amita Gupta, Savita Pahwa

Prevalence of depression among postpartum women on Isoniazid-Preventive Therapy and Efavirenz-based treatment for HIV—An exploratory objective of the IMPAACT P1078 randomized trial

Conference

IAS 2021

Study

P1078

Authors

Kristin Baltrusaitis, Lynda Stranix-Chibanda, Grace Montepiedra, Lisa Aaron, Jyoti Mathad, Carol Onyango, Patricia Mandima, Mandisa Nyati, James Ngocho, Gift Chareka, Ponego Ponetshego, Gaerolwe Masheto, Katie McCarthy, Patrick Jean-Phillippe, Amita Gupta, IMPAACT P1078 study team